We examined the relationship between vitamin D intake and breast cancer, delving into how this vitamin may play a role in prevention and management. The findings suggest that vitamin D may have a protective effect, potentially lowering the risk of developing breast cancer.
While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.
Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.
Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
Read More
8
Vitamin D impacts breast cancer outcomes
Impact of Vitamin D Levels on Progression-Free Survival and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Systematic Review and Meta-Analysis.
We explored how vitamin D (VD) levels might impact breast cancer (BC) patients undergoing neoadjuvant chemotherapy (NACT). The study reviewed data from six different research projects involving patients who had confirmed diagnoses of BC and had their vitamin D levels measured before starting chemotherapy.
Our analysis revealed some intriguing findings. Specifically, maintaining adequate vitamin D levels appeared to lower the chances of not responding to neoadjuvant chemotherapy by 22%. Additionally, those with sufficient vitamin D experienced a 35% reduced risk of disease progression compared to those with low or deficient levels. This suggests that vitamin D might play a beneficial role in improving treatment outcomes for breast cancer patients.
Overall, these results underscore the importance of keeping vitamin D levels within a healthy range during cancer treatment. They encourage us to delve deeper into how vitamin D influences cancer biology and its potential as a supportive therapy in breast cancer management.
Read More
5
Vitamin D's impact on muscle strength
Low Serum Vitamin D Levels Are Associated with Reduced Muscle Strength in Women with Breast Cancer.
We explored the connection between vitamin D levels and muscle strength in women with breast cancer. This research involved adult women who had been diagnosed with breast cancer within the last 12 months, ensuring that none had metastases or recurrences. Our focus was on understanding how inadequate vitamin D might relate to reduced muscle strength in this specific group.
We discovered that a significant portion of the participants, around 70%, had insufficient levels of vitamin D. This deficiency was notably linked to lower muscle strength, as indicated by the Handgrip Strength test. Specifically, the findings showed that women with insufficient vitamin D were more likely to fall into the lower muscle strength categories.
The study sheds light on the importance of monitoring vitamin D levels in women battling breast cancer. Given the link between low vitamin D and weaker muscle strength, addressing this deficiency might offer a new avenue for improving overall health and vitality in these patients.
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Most Useful Reviews
7.5
Good gut health
1 people found this helpful
I was satisfied as it did a great job for my baby and offered an excellent price for the servings provided. It helped establish good gut health and alleviated gas, colic, and reflux. I highly recommend it for infants since they are born with a sterile digestive system. While it can be a bit tricky to administer, breastfeeding mothers might find it easier to give a few drops on the breast.
Read More
0
Did not help
1 people found this helpful
I had high hopes for this remedy, as my baby suffered from severe colic, but it didn't work at all, and the colic got worse. I read that it only helps if the baby is given breast milk, however, my son was also on formula.
Read More
7.5
Improved stool consistency
I've received it well! I believe it's even better with vitamin D. After consuming breast milk, there was a significant improvement in my baby’s bowel movements. Overall, it has helped in wrapping things up and I’ve noticed much better outcomes after eating this!
We examined the relationship between vitamin D intake and breast cancer, delving into how this vitamin may play a role in prevention and management. The findings suggest that vitamin D may have a protective effect, potentially lowering the risk of developing breast cancer.
While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.
Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.
Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
Read More
8
Vitamin D's potential in breast cancer
FAP-targeting biomimetic nanosystem to restore the activated cancer-associated fibroblasts to quiescent state for breast cancer radiotherapy.
We explored the role of vitamin D, specifically calcipotriol, in targeting cancer-associated fibroblasts (CAFs) within the breast cancer microenvironment. CAFs are crucial players in tumor behavior, influencing growth, recurrence, and treatment resistance.
Our study introduced a cutting-edge nanosystem designed to deliver calcipotriol directly to activated CAFs. This approach aimed to transition these cells back to a quiescent state, curtailing their contributions to tumor progression and boosting immune responses against tumors.
When we tested this strategy, we discovered that calcipotriol effectively activated the vitamin D receptors on CAFs. This activation encouraged a shift away from a pro-tumor environment. Moreover, by combining our treatment with radiotherapy, we significantly enhanced the sensitivity of tumors to radiation while increasing the presence of cytotoxic T cells in the tumor area.
Ultimately, the findings suggest that this vitamin D treatment, packaged in a biomimetic nanosystem, has promising potential for improving breast cancer therapies. It not only assists in modifying the behavior of supportive cells in tumors but also boosts the body's immune response.
Read More
8
Vitamin D impacts breast cancer outcomes
Impact of Vitamin D Levels on Progression-Free Survival and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Systematic Review and Meta-Analysis.
We explored how vitamin D (VD) levels might impact breast cancer (BC) patients undergoing neoadjuvant chemotherapy (NACT). The study reviewed data from six different research projects involving patients who had confirmed diagnoses of BC and had their vitamin D levels measured before starting chemotherapy.
Our analysis revealed some intriguing findings. Specifically, maintaining adequate vitamin D levels appeared to lower the chances of not responding to neoadjuvant chemotherapy by 22%. Additionally, those with sufficient vitamin D experienced a 35% reduced risk of disease progression compared to those with low or deficient levels. This suggests that vitamin D might play a beneficial role in improving treatment outcomes for breast cancer patients.
Overall, these results underscore the importance of keeping vitamin D levels within a healthy range during cancer treatment. They encourage us to delve deeper into how vitamin D influences cancer biology and its potential as a supportive therapy in breast cancer management.
Read More
8
Vitamin D aids breast cancer nutrition
The Effects of Omega-3 Fatty Acids and Vitamin D Supplementation on the Nutritional Status of Women with Breast Cancer in Palestine: An Open-Label Randomized Controlled Trial.
We focused on the effect of vitamin D treatment, alongside omega-3 fatty acids, on the nutritional status of women newly diagnosed with breast cancer in Palestine. In this study, 88 participants were divided into four groups: one receiving omega-3 supplements, another getting vitamin D, a third combining both, and a control group without active treatment.
Over a nine-week period, we provided patients with daily omega-3 capsules and weekly vitamin D tablets. After this intervention, we measured the participants' nutritional status using various tools, including the Patient-Generated Subjective Global Assessment (PG-SGA) which helped us gauge changes in their wellbeing.
Our results showed that women who received the combined omega-3 and vitamin D supplementation experienced improvements in their nutritional status. This was evident through better PG-SGA scores, favorable changes in anthropometric measurements, and enhanced blood albumin levels, along with increases in dietary energy and protein intake.
Overall, this indicates that introducing vitamin D and omega-3 fatty acids can support nutritional health during breast cancer treatments, yet the specific effects of vitamin D alone remain intertwined with those of omega-3 supplementation.
Read More
8
Vitamin D improves life quality
The effects of Omega-3 fatty acids and vitamin D supplementation on the quality of life and blood inflammation markers in newly diagnosed breast cancer women: An open-labelled randomised controlled trial.
We conducted a study to explore the effects of vitamin D and omega-3 fatty acids on the quality of life of women newly diagnosed with breast cancer. Our research involved 88 participants who were randomly assigned to one of four groups. Each group received either omega-3 supplements, vitamin D, a combination of both, or no supplementation at all for a period of nine weeks.
Throughout the study, we assessed the women's quality of life using specific questionnaires and measured markers of inflammation in their blood. Our main aim was to see if vitamin D could play a beneficial role alongside omega-3 in improving health outcomes during their chemotherapy treatment.
The results showed that those taking vitamin D, whether alone or with omega-3, reported a significant improvement in their quality of life as well as reductions in inflammation markers. This indicates that vitamin D may have a positive impact on the overall health status and well-being of women facing the challenges of breast cancer treatment.
I was satisfied as it did a great job for my baby and offered an excellent price for the servings provided. It helped establish good gut health and alleviated gas, colic, and reflux. I highly recommend it for infants since they are born with a sterile digestive system. While it can be a bit tricky to administer, breastfeeding mothers might find it easier to give a few drops on the breast.
Read More
0
Did not help
1 people found this helpful
I had high hopes for this remedy, as my baby suffered from severe colic, but it didn't work at all, and the colic got worse. I read that it only helps if the baby is given breast milk, however, my son was also on formula.
Read More
7.5
Improved stool consistency
I've received it well! I believe it's even better with vitamin D. After consuming breast milk, there was a significant improvement in my baby’s bowel movements. Overall, it has helped in wrapping things up and I’ve noticed much better outcomes after eating this!
Read More
Frequently Asked Questions
Breast cancer is a type of cancer that originates in the breast tissue, most commonly in the ducts or lobules. It occurs when the cells in the breast grow uncontrollably, forming a tumor that can be detected through physical examination or mammography. Various factors contribute to the risk of developing breast cancer, including age, family history, genetic mutations, and lifestyle choices such as diet and exercise. Breast cancer can manifest in different forms, with invasive ductal carcinoma being the most prevalent type.
Treatment for breast cancer typically involves a combination of surgery, radiation therapy, chemotherapy, and hormone therapy, tailored to the specific diagnosis and stage of the disease. Early detection through regular screening can significantly improve the prognosis, as it allows for timely intervention. Advances in research and treatment have led to increased survival rates, making awareness and education about breast cancer crucial for early diagnosis and effective management.
Children's probiotics are dietary supplements specifically formulated to provide beneficial bacteria that support digestive health and the immune system in children. These probiotics contain various strains of live microorganisms, often including Lactobacillus and Bifidobacterium, which are known to help maintain a healthy balance of gut bacteria. The gut microbiome plays a crucial role in children's overall health, influencing their digestion, immune function, and even mood. Many parents turn to children's probiotics to help address issues like constipation, diarrhea, or colic, as well as to support their child’s immunity, especially during cold and flu season.
When selecting a children's probiotic, it’s essential to consider factors such as the specific strains included, the number of colony-forming units (CFUs), and whether it is tailored to your child's specific health needs. Probiotics can come in various forms, including powders, gummies, and liquids, making them easy to administer to little ones. However, it’s always advisable to consult a pediatrician before starting any new supplement regime for your child, as they can provide personalized recommendations based on the child's health history and current needs.
The connection between vitamin D supplementation and breast cancer is backed by a growing body of scientific research, although more rigorous studies are needed to fully understand its implications in treatment and prevention. For instance, one study found that women with breast cancer had significantly lower levels of vitamin D compared to those without the disease, suggesting that vitamin D deficiency may be a potential risk factor for developing breast cancer [5]. Moreover, another investigation indicated that adequate vitamin D levels could potentially improve treatment outcomes in breast cancer patients undergoing chemotherapy, linking low vitamin D levels with poorer responses to treatment [6].
Though these findings are promising, challenges remain in definitively establishing vitamin D's protective effects against breast cancer due to the observational nature of much existing research. A study highlighted the critical role of vitamin D in managing symptoms like cachexia during chemotherapy, linking severe deficiency to an increased risk of health complications [4]. Furthermore, while vitamin D has shown potential benefits in modifying tumor behavior and enhancing immune responses, its exact role in breast cancer management requires further investigation [7]. Thus, while vitamin D supplementation may be advantageous for some breast cancer patients, individuals should consult healthcare providers to tailor treatment plans based on the latest scientific insights.
Users have reported varying degrees of improvement in their babies' symptoms after using the product. For instance, one user noted significant benefits such as alleviation of gas, colic, and reflux, emphasizing that it was effective in establishing good gut health for their infant Read Review. This aligns with positive experiences shared by others who observed enhanced bowel movements and overall better outcomes when the product was combined with breast milk Read Review.
Conversely, some parents reported that the remedy didn't work for their infants, particularly in cases involving severe colic accompanied by formula feeding Read Review. These mixed results underscore the fact that while many users found success, individual experiences can vary widely depending on factors such as the type of feeding and the specific digestive issues encountered. As with any product related to infant care, it may be essential for parents to assess their child's unique needs and consult with healthcare professionals for the best possible outcomes.
7.5
Good gut health
1 people found this helpful
I was satisfied as it did a great job for my baby and offered an excellent price for the servings provided. It helped establish good gut health and alleviated gas, colic, and reflux. I highly recommend it for infants since they are born with a sterile digestive system. While it can be a bit tricky to administer, breastfeeding mothers might find it easier to give a few drops on the breast.
7.5
Improved stool consistency
I've received it well! I believe it's even better with vitamin D. After consuming breast milk, there was a significant improvement in my baby’s bowel movements. Overall, it has helped in wrapping things up and I’ve noticed much better outcomes after eating this!
0
Did not help
1 people found this helpful
I had high hopes for this remedy, as my baby suffered from severe colic, but it didn't work at all, and the colic got worse. I read that it only helps if the baby is given breast milk, however, my son was also on formula.
5
Vitamin D's role in breast cancer
The status of serum 25(OH)D levels is related to breast cancer.
Our study focused on the potential link between vitamin D levels and breast cancer among women. We conducted a cross-sectional analysis involving 40 women diagnosed with breast cancer and compared their serum vitamin D levels to a matched control group of 40 women without the disease.
The results were quite compelling. We found that the average levels of vitamin D were significantly lower in women with breast cancer, which raises interesting questions about vitamin D deficiency as a risk factor for this cancer. Specifically, women with breast cancer averaged about 31.9 ng/mL of vitamin D, while those without the disease measured around 37.98 ng/mL.
Notably, half of the women in the breast cancer group were found to be vitamin D deficient, whereas only 27.5% of the control group faced the same issue. Additionally, we observed a correlation between lower vitamin D levels and various socio-economic factors among breast cancer patients.
While these findings suggest a potential connection between low vitamin D levels and breast cancer risk, it’s essential to approach this topic with cautious optimism. Further research is needed to fully understand this relationship and the possible benefits of vitamin D enrichment on breast cancer prevention.
7
Vitamin D's role in chemotherapy response
Pretreatment plasma vitamin D and response to neoadjuvant chemotherapy in breast cancer: evidence from pooled analysis of cohort studies.
We explored the relationship between vitamin D levels before treatment and the effectiveness of neoadjuvant chemotherapy (NAC) in breast cancer patients. This analysis pooled data from a variety of studies to assess whether low vitamin D levels could influence how well patients respond to chemotherapy and subsequently their survival.
The findings suggest that having low vitamin D before starting treatment is linked to a poorer response to NAC. Specifically, patients with vitamin D deficiency showed a lower likelihood of achieving what is known as a pathological complete response (pCR), which means no signs of cancer were detected post-treatment. The study highlights the potential role of vitamin D in enhancing treatment responses and improving patient outcomes, although it calls for further research to solidify these claims.
Thus, while we see a concerning trend indicating low vitamin D levels may hinder chemotherapy effectiveness in breast cancer, more extensive studies are necessary before advising vitamin D supplementation as a strategy to improve treatment outcomes. This thoughtful approach ensures that any recommendations are backed by solid evidence.
4
Vitamin D's role in cachexia
Severe Deficiency of Vitamin D and Anthracycline-Taxane Regimen are associated with Cachexia Following Breast Cancer Chemotherapy: A Single Center Assessment Using Two Consensus-Based Criteria.
We assessed the impact of vitamin D levels on breast cancer patients undergoing chemotherapy, focusing on cachexia—a condition that leads to weight loss and muscle wasting, often seen in cancer patients. Our study analyzed 160 women who started chemotherapy between July 2018 and June 2022.
Through examining various factors such as age, body mass index, and chemotherapy regimens, we discovered that a significant portion of participants experienced cachexia during treatment. Notably, all patients demonstrated deficient vitamin D levels at baseline, with severe deficiency linked to a greater risk of cachexia.
We found that those with the severe deficiency (vitamin D levels below 8.94 ng/mL) faced a higher likelihood of developing cachexia, alongside the type of chemotherapy regimen administered. Specifically, the anthracycline-taxane regimen was distinctly associated with increased cachexia risk according to our findings.
These results highlight the critical role of vitamin D not just in bone health but also in the complex landscape of cancer treatment and recovery. Our study suggests that addressing vitamin D deficiency, perhaps through supplementation, could be an important consideration for improving patient outcomes and mitigating the effects of cachexia during chemotherapy.
8
Vitamin D's potential in breast cancer
FAP-targeting biomimetic nanosystem to restore the activated cancer-associated fibroblasts to quiescent state for breast cancer radiotherapy.
We explored the role of vitamin D, specifically calcipotriol, in targeting cancer-associated fibroblasts (CAFs) within the breast cancer microenvironment. CAFs are crucial players in tumor behavior, influencing growth, recurrence, and treatment resistance.
Our study introduced a cutting-edge nanosystem designed to deliver calcipotriol directly to activated CAFs. This approach aimed to transition these cells back to a quiescent state, curtailing their contributions to tumor progression and boosting immune responses against tumors.
When we tested this strategy, we discovered that calcipotriol effectively activated the vitamin D receptors on CAFs. This activation encouraged a shift away from a pro-tumor environment. Moreover, by combining our treatment with radiotherapy, we significantly enhanced the sensitivity of tumors to radiation while increasing the presence of cytotoxic T cells in the tumor area.
Ultimately, the findings suggest that this vitamin D treatment, packaged in a biomimetic nanosystem, has promising potential for improving breast cancer therapies. It not only assists in modifying the behavior of supportive cells in tumors but also boosts the body's immune response.
References
Schömann-Finck M, Vogt T, Reichrath J. Umbrella Review on the Relationship Between Vitamin D Intake and Cancer. Anticancer Res. 2025;45:855. doi:10.21873/anticanres.17474
Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. doi:10.7759/cureus.78283
Pereira da Silva Garcia MR, Rechinelli AB, Minto Dos Santos D, Abdala Nogueira Souza J, Barcellos Leite da Silva L, et al. Low Serum Vitamin D Levels Are Associated with Reduced Muscle Strength in Women with Breast Cancer. Nutr Cancer. 2025. doi:10.1080/01635581.2025.2471621
Hutajulu SH, Aresy S, Astari YK, Wiranata JA, Puspitaningtyas H, et al. Severe Deficiency of Vitamin D and Anthracycline-Taxane Regimen are associated with Cachexia Following Breast Cancer Chemotherapy: A Single Center Assessment Using Two Consensus-Based Criteria. Asian Pac J Cancer Prev. 2025;26:189. doi:10.31557/APJCP.2025.26.1.189
Momivand M, Razaghi M, Mohammadi F, Hoseinzadeh E, Najafi-Vosough R. The status of serum 25(OH)D levels is related to breast cancer. Cancer Treat Res Commun. 2024;42:100870. doi:10.1016/j.ctarc.2025.100870
Shu C, Yang Q, Huang J, Xie X, Li H, et al. Pretreatment plasma vitamin D and response to neoadjuvant chemotherapy in breast cancer: evidence from pooled analysis of cohort studies. Int J Surg. 2024;110:8126. doi:10.1097/JS9.0000000000002142
Gao C, Jian C, Wang L, Liu Y, Xiong Y, et al. FAP-targeting biomimetic nanosystem to restore the activated cancer-associated fibroblasts to quiescent state for breast cancer radiotherapy. Int J Pharm. 2025;670:125190. doi:10.1016/j.ijpharm.2025.125190
Ottaiano A, Facchini BA, Iacovino M, Santorsola M, Facchini S, et al. Impact of Vitamin D Levels on Progression-Free Survival and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Cancers (Basel). 2024;16. doi:10.3390/cancers16244206
Almassri HF, Abdul Kadir A, Srour M, Foo LH. The Effects of Omega-3 Fatty Acids and Vitamin D Supplementation on the Nutritional Status of Women with Breast Cancer in Palestine: An Open-Label Randomized Controlled Trial. Nutrients. 2024;16. doi:10.3390/nu16223960
Bissan ADT, Amegonou AEH, Sidibé FM, Ly M, Barry NOK, et al. [Vitamin D Deficiency In Advanced Breast Cancer Risk In Mali]. Mali Med. 2024;39:50.
Almassri HF, Abdul Kadir A, Srour M, Foo LH. The effects of Omega-3 fatty acids and vitamin D supplementation on the quality of life and blood inflammation markers in newly diagnosed breast cancer women: An open-labelled randomised controlled trial. Clin Nutr ESPEN. 2025;65:64. doi:10.1016/j.clnesp.2024.11.014
Abdollahi S, Vahdat M, Saeedirad Z, Mahmoudi Z, Torkaman M, et al. Multifaceted Role of Vitamin D in Breast Cancer: A Systematic Review of Genetic and Pathway-Based Mechanisms. Asian Pac J Cancer Prev. 2024;25:3349. doi:10.31557/APJCP.2024.25.10.3349
Wu S, Ma XD, Zhang XM, Shi C, Du KY, et al. Genetic evidence supporting the causal role of 25-hydroxyvitamin D levels in the prognosis of ER- breast cancer: A Mendelian randomization study. Medicine (Baltimore). 2024;103:e40262. doi:10.1097/MD.0000000000040262
Yum C, Andolino C, Larrick B, Sheeley MP, Teegarden D. 1α,25-Dihydroxyvitamin D Downregulates Adipocyte Impact on Breast Cancer Cell Migration and Adipokine Release. Nutrients. 2024;16. doi:10.3390/nu16183153
Stachowicz-Suhs M, Łabędź N, Milczarek M, Kłopotowska D, Filip-Psurska B, et al. Vitamin D reduces the expression of M1 and M2 macrophage markers in breast cancer patients. Sci Rep. 2024;14:22126. doi:10.1038/s41598-024-73152-x
Tirgar A, Rezaei M, Ehsani M, Salmani Z, Rastegari A, et al. Exploring the synergistic effects of vitamin D and synbiotics on cytokines profile, and treatment response in breast cancer: a pilot randomized clinical trial. Sci Rep. 2024;14:21372. doi:10.1038/s41598-024-72172-x